2026
21) Yogita Martoliya, Sudharsan Mathivathanan, Dhrumi Shah, Ashish Shrivastava, Shailendra Asthana and Sriram Varahan#. 2026. Systematic Screening of a Glycolysis-targeting Small-molecule Library Identifies Novel Inhibitors of Fungal Morphogenesis in Candida albicans. bioRxiv. 2026.04.23.720332; doi: https://doi.org/10.64898/2026.04.23.720332 (# - Corresponding Author)
20) Pallavi S Phatak, Sudharsan Mathivathanan, Ishvarya Suresh, Mary Shejo and Sriram Varahan#. 2026. A Conserved Metabolic Network Orchestrates Melanin-Dependent Titan Cell Formation in Cryptococcus neoformans. bioRxiv. 2025.09.02.673682; doi: https://doi.org/10.1101/2025.0902.673682 (# - Corresponding Author)
19) Dhrumi Shah, Nikita Rewatkar, Adishree M, Siddhi Gupta, Sudharsan Mathivathanan, Sayantani Biswas and Sriram Varahan#. Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi. eLife. 2026 Feb doi: https://doi.org/10.7554/eLife.109075. (# - Corresponding Author)
2025
18) Soumya Kundu, Swati Chauhan, Kollori Dhar, Sriram Varahan#, Santosh Chauhan#. 2025. Chats and Spats of Autophagy and Innate Immune Systems. J Mol Biol. Aug 11:169387. doi: 10.1016/j.jmb.2025.169387. (# - Corresponding Author)
2024
17) Dhrumi Shah and Sriram Varahan#. Enterococcus faecalis. Trends in Microbiology. 2024 May 17:S0966-842X(24)00095-7. doi: 10.1016/j.tim.2024.04.010. (# - Corresponding Author)
16) Vineeth Vengayil, Shreyas Niphadkar, Swagata Adhikary, Sriram Varahan and Sunil Laxman. The deubiquitinase Ubp3/Usp10 constrains glucose-mediated mitochondrial repression via phosphate budgeting. eLife. 12:RP90293. https://doi.org/ 10.7554/eLife.90293.4
2023
15) Sriram Varahan#. Unity in Diversity: Interkingdom Polymicrobial Biofilms in Disease. In: Kaushik, K.S., Darch, S.E. (eds) Multispecies Biofilms. Springer Series on Biofilms, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-031-15349-5_9. (# - Corresponding Author)
2021
14) Sriram Varahan# and Sunil Laxman#. Bend or break: how biochemically versatile molecules enable metabolic division of labor in clonal microbial communities. Genetics. 219(2):iyab109.doi: 10.1093/genetics/iyab109. (# - Corresponding Author)
13) Srivatsan Parthasarathy, Xiaofei Wang, Kristen Carr, Sriram Varahan and Lynn Hancock. SigV mediates lysozyme resistance in Enterococcus faecalis via RsiV and PgdA. Journal of Bacteriology. 203(20):e0025821.doi: 10.1128/JB.00258-21.
12) Erica Keffeler, Vijayalakshmi Iyer, Srivatsan Parthasarathy, Matthew Ramsey, Matthew Gorman, Theresa Barke, Sriram Varahan, Sally Olson, Michael Gilmore, Zakria Abdullahi, Emmaleigh Hancock, and Lynn Hancock. Influence of the alternate sigma factor RpoN on global gene expression and carbon catabolism in Enterococcus faecalis V583. mBio. 12(3):e00380-21.doi: 10.1128/mBio.00380-21.
2020
11) Sriram Varahan, Vaibhhav Sinha, Adhish Walvekar, Sandeep Krishna and Sunil Laxman. Resource plasticity driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community. eLife. Sep 2;9:e57609.doi: 10.7554/eLife.57609.
Spotlight:
1) India Alliance Fellow's Research
2) DBT-InStem Research Spotlight
10) Srivatsan Parthasarathy, Lorne Jordan, Nancy Schwarting, Megan Woods, Zakria Abdullahi, Sriram Varahan, Patricia Passos, Brandy Miller and Lynn Hancock. Involvement of chromosomally encoded homologs of the RRNPP protein family in Enterococcus faecalis biofilm formation and UTI pathogenesis. Journal of Bacteriology. Aug 10;202(17):e00063-20.doi: 10.1128/JB.00063-20.
9) Anirudh Chakravarthy, Srikar Krishna, Sumana Ghosh, Ajay Tomar, Sriram Varahan, Ajit Rajwade, Sabyasachi Ghosh et al. Large-scale testing using Tapestry pooling. medRxiv.doi: https://doi.org/10.1101/2020.10.09.20209742. (Preprint)
8) Sabyasachi Ghosh, Ajit Rajwade, Srikar Krishna, Nikhil Gopalkrishnan, Thomas E Schaus, Anirudh Chakravarthy, Sriram Varahan, Vidhya Appu et al. Tapestry: A Single-Round Smart Pooling Technique for COVID-19 Testing. medRxiv. doi:https://doi.org/10. 1101/ 2020.04.23.20077727.
Spotlight: The HINDU (Newspaper)
2019
7) Sriram Varahan, Adhish Walvekar, Vaibhhav Sinha, Sandeep Krishna and Sunil Laxman. Metabolic constraints drive self-organization of specialized cell groups. Elife. June 26;8. pii: e46735.doi: 10.7554/eLife.46735. Faculty Opinions Recommended
Spotlight:
1) eLife Digest
2) India Alliance Fellow's Research
3) DBT-InStem Research Spotlight:
4) The HINDU (Newspaper)
2016
6) Sriram Varahan and Lynn Hancock. To defend or not to defend: That’s the question. mSphere. 1(3):e00127-16. doi:10.1128/mSphere.00127-16.
2015
5) Michael Gilmore, Marcus Rauch, Matthew Ramsey, Paul Himes, Sriram Varahan, Janot Manson, Francois Lebreton and Lynn Hancock. Pheromone killing of multidrug resistant Enterococcus faecalis strain V583 by commensal strains. Proc Natl Acad Sci U S A. Jun 9;112(23):7273-8.
2014
4) Sriram Varahan, Nathan Harms, John Tomich, Michael Gilmore and Lynn Hancock. An ABC transporter is required for secretion of peptide sex pheromones in Enterococcus faecalis. mBio. 5(5):e01726-14.doi:10.1128/mBio.01726-14.
2013
3) Neuza Teixeira, Sriram Varahan, Matthew Gorman, Kelli Palmer, et al. Drosophila host model reveals new Enterococcus faecalis quorum-sensing associated virulence factors. PLOS ONE. May;8(5):e64740.doi:10.1371/journal.pone.0064740.
2) Sriram Varahan, Vijayalakshmi Iyer, William Moore and Lynn Hancock. Eep confers lysozyme resistance to Enterococcus faecalis via the activation of the ECF sigma factor, SigV. Journal of Bacteriology. Jul;195(14):3125-34.doi:10.1128/JB.00291-13.
Spotlight: Kansas State University Spotlight
2012
1) Stephanie Shishido*, Sriram Varahan*, Kai Yuan*, Xiangdong Li* and Sherry Fleming. Humoral Innate Immune Response and Disease. Clinical Immunology. Aug;144(2):142-58.doi: 10.1016/j.clim.2012.06.002. (* - Authors contributed equally)
